Semaglutide

Semaglutide GLP-1

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which helps the body to regulate its glucose levels and suppress appetite. GLP-1 is an enzyme that helps the pancreas release insulin when needed, especially after you eat, reducing your blood sugar levels. Semaglutide also reduces appetite by increasing satiety hormones like cholecystokinin (CCK) and glucagon-like peptide 1 (GLP-1), in addition to lowering the hormone ghrelin, which triggers hunger.

Semaglutide VS. Phentermine

Semaglutide and phentermine are both prescribed for weight loss. However, semaglutide is an injectable medication that controls appetite whereas phentermine is an oral pill that works as a stimulant to increase metabolism and reduce calorie intake. While phentermine is typically used for short-term weight loss, semaglutide is usually prescribed for long-term use. Semaglutide has been shown to have fewer side effects than phentermine and may be more effective at helping people achieve sustained weight loss.

Benefits :

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Reduced appetite
Controls apetite and reduces craving for food.
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Increased satiety hormones
Ghrelin and Leptins controls hunger sensation.
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Slowed Digestion
Induces longer breaks between food intake.
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Improved glucose regulation
Regulates right amount of glucagon & insulin to trigger weight loss.
 
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Long-term weight loss results
The resultant weight loss persists longer than other methods.
 

 

 

Commonly asked questions:

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What is Semaglutide?
Semaglutide (the active ingredient in Novo Nordisk’s Ozempic® and Wegovy® drug products)– is an injectable medication which, when used in combination with diet and exercise, helps with blood sugar control, appetite control, and potential weight loss. Semaglutide belongs to a class of medications called glucagon-like peptide-1 (GLP-1) agonists, which mimic the hormone GLP-1 in your body to lower blood sugar levels after you’ve eaten a meal.
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What is the hormone GLP-1?
Glucagon-like peptide 1 (GLP-1) is a hormone that causes huge effects on the regulation of blood sugar by stimulating glucose-dependent insulin secretion. Insulin is a hormone that promotes sugar uptake by the cells, stores sugar as glycogen, promotes the building of fat, and signals the body to build skeletal muscle. In addition, GLP-1 inhibits glucagon release (which slows down the release of sugar into the blood so that you burn more fat), slows down gastric emptying (makes you feel full), and lowers the desire for food intake (because you feel full).
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Is Semaglutide a stimulant?
No, semaglutide is not a stimulant. While other weight loss medications, like phentermine, have stimulating effects that curb your appetite, semaglutide works very differently (see above).
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What does Semaglutide induce weight loss?
GLP-1 agonists like semaglutide help to control your blood sugar, curb your appetite, and slow digestion. People taking them also tend to lose weight. GLP-1, the key hormone involved, slows the process of gastric emptying. In addition to causing your pancreas to release insulin, semaglutide also blocks a hormone that causes your liver to release sugar (glucagon). Together, these functions can help decrease your appetite, causing you to eat less food and lose more weight.
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Does Semaglutide curb your appetite?
Yes, it is believed that semaglutide can help curb your appetite. In addition to slowing gastric emptying to make you feel full for a longer period of time, GLP-1 also plays a direct role in appetite regulation.
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How long does it take to lose weight on Wegovy® (Semaglutide)?
With semaglutide, you will slowly work your way up to the target dose at which time you will see the most amount of weight loss. This was the case in the clinical trials of Novo Nordisk’s Wegovy® (semaglutide) drug product, where participants had their dose adjusted until they reached 2.4mg once weekly. During the phase 3 trial that measured outcomes at 20 weeks, most participants were able to reach the full dose and lost more weight as their dose was increased. They saw additional weight loss over the remaining 48 weeks at the full dose. It is important to keep in mind that patients will see the best results when medication is taken in combination with a healthy diet and exercise.
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Is Semaglutide safe?
Semiglutidedrug products are considered to be safe and effective when used as indicated by the FDA. Semaglutide, the active ingredient in Novo Nordisk’s Ozempic® and Wegovy® drug products, still may have possible side effects. Possible side effects include nausea, vomiting, or diarrhea. Semaglutide also may cause thyroid C-cell tumors in rodents (with unknown risk shown in humans). Thus, semaglutide shouldn’t be used if you or your family have a history of certain thyroid cancers. Semaglutide should not be used in people with type-1 diabetes or a history of pancreatitis. Semaglutide should be used cautiously for people on other blood sugar lowering medications. ** Note: ** Compounded semaglutide has not been FDA tested or approved for safety, efficacy or quality.
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Where will I receive my Wegovy® (Semaglutide) drug product or Compounded Semaglutide?
Once enrolled in the program and evaluated by one of our providers, your prescription will be sent to the pharmacy of your choice or, for compounded semaglutide, will ship directly to our office where you can come in weekly for your dosage, or can be shipped directly to your home.
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What is the dose of Semaglutide?
Dosing for semglutidedrug product starts at .5mg injected once weekly and goes up to 2.4mg injected once weekly. Dosing for compounded semaglutide starts a .5mg injected once weekly and goes up to 2.5mg injected once weekly
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Are there any foods or medications you should avoid while on compounded semaglutide?
First, you’ll want to limit how much alcohol you’re drinking while taking compounded semaglutide . Alcohol tends to have an effect on your blood sugar, and there is a risk that it may drop too low in combination with semaglutide, especially if you are drinking on an empty stomach.You will want to make sure your provider is aware of any other medications you are taking before starting semaglutide.
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What is the dose of Semaglutide?
The most common side effects of semaglutide are:
  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach pain
  • Constipation